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Free, publicly-accessible full text available August 1, 2026
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Taylor, Andrew D; Hathaway, Quincy A; Kunovac, Amina; Pinti, Mark V; Newman, Mackenzie S; Cook, Chris C; Cramer, Evan R; Starcovic, Sarah A; Winters, Michael T; Westemeier-Rice, Emily S; et al (, American Journal of Physiology-Cell Physiology)Long noncoding RNAs (lncRNAs) are relatively novel RNAs with increasingly prominent roles in regulating genetic expression, mainly in the nucleus but more recently in regions such as the mitochondrion. This study explores how lncRNAs interact with polynucleotide phosphorylase (PNPase), a protein that regulates RNA import into the mitochondrion. Machine learning identified several RNA structural features that improved lncRNA binding to PNPase, which may be useful in targeting RNA therapeutics to the mitochondrion.more » « less
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Farrelly, Colleen; Singh, Yashbir; Hathaway, Quincy A; Carlsson, Gunnar; Choudhary, Ashok; Paul, Rahul; Doretto, Gianfranco; Himeur, Yassine; Atalls, Shadi; Mansoor, Wathiq (, IEEE)
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Hathaway, Quincy A.; Yanamala, Naveena; Siva, Nanda K.; Adjeroh, Donald A.; Hollander, John M.; Sengupta, Partho P. (, Journal of the American College of Cardiology)
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